U1-70k Antibody 203 011 from Synaptic Systems GmbH

Product Specs
ItemU1-70k Antibody
CompanySynaptic Systems GmbH
Price Supplier Page View Company Product Page
Catalog Number203 011
Quantity100 µg
ApplicationsWB, IHC_P, ICC, IP, IHC, FACS
Conjugate/TagUnconjugated
TargetU1-70k
IsotypeIgG2a
Hostmouse
Formatpurified IgG
Reactivityhuman, rat, mouse, mammals
Brand/TrademarkSynaptic Systems
Clonalitymonoclonal
Cell LineH111
CloneH111
ImmunogenRecombinant protein corresponding to AA 1 to 437 from human U1-70k
NCBI Full Gene Namesmall nuclear ribonucleoprotein U1 subunit 70
NCBI Gene AliasesRNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP

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Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) Stimulus-specific remodeling of the neuronal transcriptome through nuclear intron-retaining transcriptsThe EMBO journalNovember 2, 2022Mazille M, Buczak K, Scheiffele P, Mauger O.Cell Signaling, 5174), anti‐MECP2 (Cell Signaling, 3456), anti‐U1‐70K (clone H111, Synaptic Systems, 203011), anti‐LAMIN B1 (Abcam, ab133741), anti‐hnRNPA1 (clone D21H11, Cell Signaling, 8443), and anti‐betaIII

(2) tRIP-seq reveals repression of premature polyadenylation by co-transcriptional FUS-U1 snRNP assemblyEMBO reportsMay 6, 2020Masuda A, Kawachi T, Takeda JI, Ohkawara B, Ito M, Ohno K.

(3) A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human CellsMolecular cellNovember 21, 2019So BR, Di C, Cai Z, Venters CC, Guo J, Oh JM, Arai C, Dreyfuss G.REAGENT or RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies U1–70K,Synaptic system,203011 U1A,Abcam,ab55751 U1C,Sigma-Aldrich,SAB4200188 SF3B1,Bethyl laboratories,A300–996A CFIm25,Proteintech,10322-AP CFIm68,Abcam,ab175237 Fip1,Bethyl laboratories

(4) Synergistic assembly of human pre-spliceosomes across introns and exonseLifeJune 22, 2018Braun JE, Friedman LJ, Gelles J, Moore MJ.endogenous protein and fSNAP-fusion protein) are listed in the table. Anti-U1-70K (Synaptic Systems, 203011, RRID:AB_887903), anti-U2B'' (American Research Products, 4G3, 03–57035), anti-Snu114 (Bethyl, A300-957A,

(5) Synergistic enhancement of production of proinflammatory cytokines of human peripheral blood monocytes by anti-Sm and anti-RNP antibodiesPloS oneJanuary 1, 2018Matsueda Y, Arinuma Y, Nagai T, Hirohata S.

(6) Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 SignalingCellDecember 14, 2017Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey JM, Yu Y, Liu X, He L, Cavaliere PM, et al.

(7) Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal developmentJournal of cell scienceFebruary 15, 2017Behm M, Wahlstedt H, Widmark A, Eriksson M, Öhman M.

(8) The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulatorsNucleic acids researchOctober 14, 2016Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, Rajgor D, Kayikci M, Feltham J, Ule J, et al.Rbp1 (sc-56767) and Gapdh (sc-25778). The remaining antibodies were U170K/Snrnp70 Synaptic Systems (203 011), Srsf1 Invitrogen (32-4500), PTBP1 Invitrogen (324800), PTBP2 (kindly provided by Michele Solimena),

(9) A 10S galectin-3-U1 snRNP complex assembles into active spliceosomesNucleic acids researchJuly 27, 2016Haudek KC, Voss PG, Wang JL, Patterson RJ.

(10) DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancerHuman molecular geneticsNovember 1, 2015Merry CR, Forrest ME, Sabers JN, Beard L, Gao XH, Hatzoglou M, Jackson MW, Wang Z, Markowitz SD, Khalil AM.

(11) SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndromeScientific reportsAugust 18, 2015Rahman MA, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, Masuda A, Engel AG, Ohno K.

(12) Detained introns are a novel, widespread class of post-transcriptionally spliced intronsGenes & developmentJanuary 1, 2015Boutz PL, Bhutkar A, Sharp PA.

(13) A novel intra-U1 snRNP cross-regulation mechanism: alternative splicing switch links U1C and U1-70K expressionPLoS geneticsJanuary 1, 2013Rösel-Hillgärtner TD, Hung LH, Khrameeva E, Le Querrec P, Gelfand MS, Bindereif A.

(14) Spatial mapping of splicing factor complexes involved in exon and intron definitionThe Journal of cell biologyJune 16, 2008Ellis JD, Llères D, Denegri M, Lamond AI, Cáceres JF.

(15) Evidence for a direct role of the disease modifier SCNM1 in splicingHuman molecular geneticsOctober 15, 2007Howell VM, Jones JM, Bergren SK, Li L, Billi AC, Avenarius MR, Meisler MH.

(16) Three-dimensional structure of a pre-catalytic human spliceosomal complex BNature structural & molecular biologyMay 1, 2004Boehringer D, Makarov EM, Sander B, Makarova OV, Kastner B, Lührmann R, Stark H.

(17) p54(nrb) associates with the 5' splice site within large transcription/splicing complexesThe EMBO journalApril 21, 2004Kameoka S, Duque P, Konarska MM.

(18) Heterogeneous nuclear ribonucleoprotein A1 interferes with the binding of the human T cell leukemia virus type 1 rex regulatory protein to its response elementThe Journal of biological chemistryMay 24, 2002Dodon MD, Hamaia S, Martin J, Gazzolo L.

(19) High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle trackingProceedings of the National Academy of Sciences of the United States of AmericaOctober 9, 2001Kues T, Dickmanns A, Lührmann R, Peters R, Kubitscheck U.

(20) A general approach for identification of RNA-protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs). Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPsThe Journal of biological chemistryDecember 29, 2000Urlaub H, Hartmuth K, Kostka S, Grelle G, Lührmann R.